By
Prof. (Mrs) E.O. Egbochuku
Introduction
Drugs are Pharmacological Agents (typically
substances) that act on humans
as biological entities. Basically Drugs are Social, Cultural, and Symbolic
"Things". Any substance that causes psychological or physiological
changes is a drug. Some things called drugs are
Psychoactive, Quite Toxic, Used Medicinally, Produce tolerance,
and Addicting whereas others are not.
So, our attempts to define Drugs are Problematic
because three main things could affect our definitions. First, social
definitions shape our understanding. Second, psychopharmacological definitions
are typically based on psycho activity; and third users’ definitions are
typically based on what gets them high.
Before we explore the problems associated with drugs and drug use, we
need to develop an understanding of the drug experience. The focus of this
article is to address this. It is hoped that people when better informed will
be armed with the raw materials necessary for informed and realistic decision
making. This article will discuss this issue in five sections:
·
Understanding
Drug Abuse and Addiction
·
What is drug addiction?
·
What happens to your brain when you take drugs?
·
Why do
some people become addicted, while others do not?
·
Prevention is the Key
Understanding Drug Abuse and
Addiction
Many people do not understand why individuals become
addicted to drugs or how drugs change the brain to foster compulsive drug
abuse. They mistakenly view drug abuse and addiction as strictly a social
problem and may characterize those who take drugs as morally weak.
One very common belief is that drug abusers should be
able to just stop taking drugs if they are only willing to change their
behaviour. What people often underestimate is the complexity of drug addiction that it is a disease that impacts the brain
and because of that, stopping drug abuse is not simply a matter of willpower.
Through scientific advances we now know much more
about how exactly drugs work in the brain, and we also know that drug addiction
can be successfully treated to help people stop abusing drugs and resume their
productive lives. This now leads us to the second issue, what is drug
addiction?
What is drug addiction?
Addiction is a chronic, often relapsing brain disease
that causes compulsive drug seeking and use despite harmful consequences to the
individual that is addicted and to those around them. Drug addiction is a brain disease because the abuse of drugs leads to changes in the
structure and function of the brain.
Although it is true that for most people the initial
decision to take drugs is voluntary, over time the changes in the brain caused
by repeated drug abuse can affect a person’s self control and ability to make
sound decisions, and at the same time It is because of these changes in the
brain that it is so challenging for a person who is addicted to stop abusing
drugs (Egbochuku 2008).
As a result of this, it is now necessary to have a look
at what happens to the brain when drug is taken. This knowledge will hopefully
assist drug users, counsellors, parents’ siblings and all stakeholders on how
best to address the issue of drug abuse.
What happens to your brain when you take
drugs?
Drugs are chemicals that tap into the brain’s
communication system and disrupt the way nerve cells normally send, receive, and process information.
There are at least two ways that drugs are able to do this:
(1) by imitating
the brain’s natural chemical messengers, and/or
(2) by over
stimulating the “reward circuit” of the brain.
Some drugs, such as heroin and marijuana, have a
similar structure to chemical messengers, called neurotransmitters, which are naturally produced by the brain.
Because of this similarity, these drugs are able to “fool” the brain’s
receptors and activate nerve cells to send abnormal messages.
Other drugs, such as cocaine or methamphetamine, can
cause the nerve cells to release abnormally large amounts of natural
neurotransmitters, or prevent the normal recycling of these brain chemicals,
which is needed to shut off the signal between neurons.
This disruption produces a greatly amplified message
that ultimately disrupts normal communication patterns. Nearly all drugs,
directly or indirectly, target the brain’s reward system by flooding the
circuit with dopamine.
Dopamine
is a neurotransmitter present in regions of the brain that control movement,
emotion, motivation, and feelings of pleasure. The over stimulation of this system, which normally
responds to natural behaviours that are linked to survival (eating, spending
time with loved ones, etc), produces euphoric (over the moon) effects in
response to the drugs.
This reaction sets in motion a pattern that “teaches”
people to repeat the behaviour of abusing drugs. As a person continues to abuse
drugs, the brain adapts to the overwhelming surges in dopamine by producing
less dopamine or by reducing the number of dopamine receptors in the reward
circuit.
As a result, dopamine’s impact on the reward circuit
is lessened, reducing the abuser’s ability to enjoy the drugs and the things
that previously brought pleasure. This decrease compels those addicted to drugs
to keep abusing drugs in order to attempt to bring their dopamine function back
to normal. And, they may now require larger amounts of the drug than they first
did to achieve the dopamine high—an effect known as tolerance.

Long-term abuse causes changes in other brain chemical
systems and circuits as well. Glutamate is a neurotransmitter that influences
the reward circuit and the ability to learn. When the optimal concentration of
glutamate is altered by drug abuse, the brain attempts to compensate, which can
impair cognitive function.
Drugs of abuse facilitate no conscious (conditioned) learning,
which leads the user to experience uncontrollable cravings when they see a place or person they associate
with the drug experience, even when the drug itself is not available. Drug-addicted
individuals show changes in areas of the brain that are critical to judgment,
decision making, learning and memory, and behaviour control. Together, these
changes can drive an abuser to seek out and take drugs compulsively despite
adverse consequences in other words, to become addicted to drugs. Yet evidence abounds
in Literature that some people do not get addicted to drugs while others do (Jaffe &
Martin, 1975; Coleman, Butcher & Carson, 1980; Egbochuku, 2000; Ogunlesi 2004).
Why do some people become addicted, while others do
not?
No single factor can predict whether or not a person
will become addicted to drugs. Risk for addiction is influenced by a person’s
biology, social environment, and age or stage of development. The more risk
factors an individual has, the greater the chance that taking drugs can lead to
addiction. For example:
Biology: The genes that people are born with in combination with environmental
influences account for about half of their addiction vulnerability.
Additionally, gender, ethnicity, and the presence of other mental disorders may
influence risk for drug abuse and addiction.
Environment: A person’s environment includes many different
influences from family and friends to socioeconomic status and quality of life
in general. Factors such as peer pressure, physical and sexual abuse, stress,
and parental involvement can greatly influence the course of drug abuse and
addiction in a person’s life (National
Drug Law Enforcement Agency, 2000).
Development: Genetic and environmental factors interact with
critical developmental stages in a person’s life to affect addiction
vulnerability, and adolescents experience a double challenge. Although taking
drugs at any age can lead to addiction, the earlier that drug use begins, the
more likely it is to progress to more serious abuse. And because adolescents’
brains are still developing in the areas that govern decision making, judgment,
and self-control, they are especially prone to risk-taking behaviours,
including trying drugs of abuse.
Prevention is the Key
Drug addiction is a preventable disease. Studies have shown that prevention programs
that involve the family, schools, communities, and the media are effective in
reducing drug abuse. Although many events and cultural factors affect drug
abuse trends, when youths perceive drug abuse as harmful, they reduce their
drug taking.
It is necessary, therefore, to help youth and the
general public to understand the risks of drug abuse and for teachers, parents,
and healthcare professionals to keep sending the message that drug addiction
can be prevented if a person never abuses drugs. Egbochuku (2008) in a lecture
delivered on behalf of Friends of Uselu Psychiatry Hospital to staff and
students of Imaguero Collage Benin City. Suggested the following preventive
measures:
Some Signs of Drug Problem
1.
Using
alcohol or drugs to:
·
help
study
·
perform
in school
·
function
the day after partying
·
decrease
stress or troubles
2. Missing Classes or Appointments
3. Having a reputation as a partier
4. Feeling guilt or remorse
5. Blacking out/Loss of memory
6. Lying about alcohol or drug use
7. Drinking or using other drugs alone
8. Thinking, "I can quit any time. I just don't want to."
How to Help a Friend
·
Let
your friend know you are concerned
·
Be a
good listener
·
Describe
how the problem affects you
·
Encourage
him/her to seek help
·
Seek
professional advice when your help is not enough
What and Where to Avoid.
·
avoid
risky situations
·
change
friends that are involved in drug use
·
get a
hobby
·
get
busy
·
the
best way is to just say no to drugs
References
Egbochuku,
E.O. (2008) How to avoid being a victim to drug abuse. A lecture delivered on
behalf of Friends of Uselu Psychiatry Hospital to staff and students of
Imaguero Collage Benin City. Tuesday 13th May, 2008
Jaffe, J. H. & Martin, W. (1975): Drug Addiction and drug
abuse, in L. S. Goodman and A Gilman (Eds.).
The Pharmacological Basis of Therapeutics (5th ed) New York, Macmillan
Coleman, J. C.; Butcher, J. N. & Carson, R. C.
(1980). Abnormal Psychology and
Modern Life. Gleriview, III: Scoth,
Foresman.
Egbochuku,
E. O. (2000) “Psychological Dependence of Drug Abuse among Secondary School
Adolescents in Nigeria:
Implications for Preventive Counselling Strategies”. Benin Journal of
Educational Studies (BJES). A
journal of the Institute of Education, University
of Benin, Benin
City. Vol 14 (1), 9-18
Weitzman, E., and Wechsler, H. (2000). Alcohol use, abuse, and
related problems among children of problem drinkers. Journal of Nervous and
Mental Diseases, 188, 148-154.
National
Drug Law Enforcement Agency, (2000). Signs, stages and Effects of Drug
Abuse, Lagos, Nigeria. Nigerian Journal of
Clinical and Counselling Psychology, 1, (2), 96 – 102.
Ogunlesi,
A.O. (2004), Patterns Of Use, Health And Other Effects Of Alcohol. Being a paper
presented at the United Nations Office On Drugs And
Crimes (Project Ad/Nir/F22) Training Workshop For Strengthening Treatment And
Rehabilitation Services Offered By Government
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